The group of Prof. Christian P. Mueller at the Psychiatric and Psychotherapeutic University Hospital of the Friedrich-Alexander-University Erlangen-Nuremberg (FAU) is offering a doctoral position (PhD) with a thematic focus on the sphingolipid neurobiology of alcohol- addiction and depression. The project investigates the role of sphingolipid regulatory enzymes in the brain in the comorbidity of alcohol addiction and depression. The goal of this project is to investigate the role of autophagy dysregulations and their control by brain sphingolipid systems in the development of alcohol addiction and/or depression in mouse models of behaviour. We will investigate how alcohol consumption affects brain sphingoliipid homeostasis (e.g. Mueller et al., Acta Neuropathologica, 2017) and how this is regulated by autophagy in emotion controlling pathways of the brain (e.g. Gulbins et al., Molecular Psychiatry, 2018). Our lab has profound expertise in neurochemical, behavioral, and molecular biological techniques related to drug addiction and depression as well as a long history in research on the neurochemical drug effects. We are looking for an enthusiastic scientist with a background in behavioral neuroscience, sphingolipid biochemistry, molecular medicine, psychology, biology, or physiology who is interested in experimental work with mice. Applicants are invited to send a copy of their curriculum vitae, list of publications, a statement of research interests and a letter of recommendation by e-mail to Christian P. Mueller (firstname.lastname@example.org).
Experience with behavioural models in rodents, e.g. with models of addiction and/or with in-vivo microdialysis or sphingolipid biochemistry would be desirable.
A good command of English (lab language) is required.
The deadline for applications is 15.01.2019!!!
Место работы: Германия
Область деятельности: Молекулярная биология (биохимия, генная инженерия)
Ph.D. Student, Erlangen (Germany) (Германия)
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